Aiming at the problem that common nonlinear Stochastic Resonance (SR) system is subject to the restriction of small parameter and is failure to detect the high frequency weak signal, a new detection method of parameter-tuning SR for weak signal with high frequency was proposed. Firstly, the relationship between the damping coefficient and the signal frequency was derived in a bistable system, and by using Kramers rate for analysis, the influence of changing damping coefficient on the SR of the system was verified. Then, the influence of SR phenomenon produced by system shape parameters was deduced, the SR of high frequency weak signal was realized through adjusting the damping coefficient and the system shape parameters, and the effect of output spectrum characteristics of the system and different sampling frequency was discussed, the stability of the algorithm was verified by the results. Finally, using the received actual signals with noise as experimental research data, the experimental results show that ultrahigh frequency weak signal under strong noise background can be extracted effectively and steadily using the strategy even when the signal frequency reaches MHz and GHz. The proposed method extends the application field of SR principle of weak signal detection.